Tag: p53 do-1

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiationResting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Little is understood about how cells regulate and combine distinct biosynthetic pathways governing differentiation and cell division. For B-lineage cells it’s broadly accepted that activated cells should full a number

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitroTargeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Intraluminal thrombus formation precipitates circumstances corresponding to acute myocardial infarction and disturbs native blood movement leading to areas of quickly altering blood movement velocities and steep gradients of blood shear