Tag: slc27a2

STAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in Mice

STAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in MiceSTAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in Mice

STAT3 prompts transcription of genes that regulate cell progress, differentiation, and survival of mammalian cells. Genetic deletion of Stat3 in T cells has been proven to abrogate Th17 differentiation, suggesting that STAT3 is a possible

Mathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin Receptor

Mathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin ReceptorMathematical Models of Blood-Brain Barrier Transport of Monoclonal Antibodies Targeting the Transferrin Receptor and the Insulin Receptor

We develop and analyze mathematical fashions for receptor-mediated transcytosis of monoclonal antibodies (MAb) focusing on the transferrin receptor (TfR) or the insulin receptor (IR), that are expressed on the blood-brain