Tag: vamp5

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiationResting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation

Little is understood about how cells regulate and combine distinct biosynthetic pathways governing differentiation and cell division. For B-lineage cells it’s broadly accepted that activated cells should full a number