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STAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in Mice

STAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in MiceSTAT3-Specific Single Domain Nanobody Inhibits Expansion of Pathogenic Th17 Responses and Suppresses Uveitis in Mice

STAT3 prompts transcription of genes that regulate cell progress, differentiation, and survival of mammalian cells. Genetic deletion of Stat3 in T cells has been proven to abrogate Th17 differentiation, suggesting that STAT3 is a possible